The release of model macromolecules may be controlled by the hydrophobicity of palmitoyl glycol chitosan hydrogels.

@article{Martin2002TheRO,
  title={The release of model macromolecules may be controlled by the hydrophobicity of palmitoyl glycol chitosan hydrogels.},
  author={Lee Martin and Clive G. Wilson and Fariba Koosha and Laurence Tetley and Alexander Ian Gray and Sevda Şenel and Ijeoma F. Uchegbu},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={2002},
  volume={80 1-3},
  pages={87-100}
}
A non-covalently cross-linked palmitoyl glycol chitosan (GCP) hydrogel has been evaluated as an erodible controlled release system for the delivery of hydrophilic macromolecules. Samples of GCP with hydrophobicity decreasing in the order GCP12>GCP11>GCP21 were synthesised and characterised by 1H NMR. Hydrogels were prepared by freeze-drying an aqueous dispersion of the polymer in the presence or absence of either a model macromolecule fluorescein isothiocyanate-dextran (FITC-dextran, MW 4400… CONTINUE READING