The release element of the yeast polymerase I transcription terminator can function independently of Reb1p.

@article{Jeong1995TheRE,
  title={The release element of the yeast polymerase I transcription terminator can function independently of Reb1p.},
  author={Soon Wuk Jeong and Weigang Lang and Ronald H. Reeder},
  journal={Molecular and cellular biology},
  year={1995},
  volume={15 11},
  pages={5929-36}
}
The Saccharomyces cerevisiae polymerase I (polI) transcription terminator utilizes a DNA-binding protein (Reb1p) as part of a signal that causes the polymerase to pause prior to release from the template. To study the release element of the terminator, independent of the Reb1p pause signal, we have replaced the Reb1p binding site with the binding site for the lac repressor, which acts as a self-contained heterologous pause signal for polI. Release efficiency is maximal when the lac repressor… CONTINUE READING

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