The relaxation mechanisms of tetrandrine on the rabbit corpus cavernosum tissue in vitro.

@article{Chen2009TheRM,
  title={The relaxation mechanisms of tetrandrine on the rabbit corpus cavernosum tissue in vitro.},
  author={Jun Chen and Jihong Liu and Tao Wang and Hengjun Xiao and Chunping Yin and Jun Yang and Xiaowen Chen and Zhangqun Ye},
  journal={Natural product research},
  year={2009},
  volume={23 2},
  pages={112-21}
}
The relaxation mechanisms of tetrandrine (Tet) on the rabbit corpus cavernosum tissue in vitro were investigated. Strips of rabbit corpus cavernosum were mounted in organ chambers. The effects of Tet were examined on isolated muscle strips pre-contracted with phenylephrine (PE) alone, in the presence of N(W)-nitro-L-arginine (LNNA, a nitric oxide synthase inhibitor), 1-H-[1,2,4]oxadiazolo[4,3-alpha]quinoxalin-1-one(ODQ, a guanylyl cyclase inhibitor), indomethacin (cyclooxygenase inhibitor… CONTINUE READING