The relative value of operon predictions

@article{Brouwer2008TheRV,
  title={The relative value of operon predictions},
  author={Rutger W. W. Brouwer and Oscar P. Kuipers and Sacha A. F. T. van Hijum},
  journal={Briefings in bioinformatics},
  year={2008},
  volume={9 5},
  pages={367-75}
}
For most organisms, computational operon predictions are the only source of genome-wide operon information. Operon prediction methods described in literature are based on (a combination of) the following five criteria: (i) intergenic distance, (ii) conserved gene clusters, (iii) functional relation, (iv) sequence elements and (v) experimental evidence. The performance estimates of operon predictions reported in literature cannot directly be compared due to differences in methods and data used… CONTINUE READING

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