The relative contributions of recombination and mutation to the divergence of clones of Neisseria meningitidis.

@article{Feil1999TheRC,
  title={The relative contributions of recombination and mutation to the divergence of clones of Neisseria meningitidis.},
  author={Edward J Feil and Martin C J Maiden and Mark Achtman and Brian G. Spratt},
  journal={Molecular biology and evolution},
  year={1999},
  volume={16 11},
  pages={1496-502}
}
Multilocus sequence typing (MLST) is a recently developed nucleotide sequence-based method for the definitive assignment of isolates within bacterial populations to specific clones. MLST uses the same principles as multilocus enzyme electrophoresis and provides data that can be used to investigate aspects of the population genetics and evolution of bacterial species. We used an MLST data set consisting of the sequences of approximately 450-bp fragments from seven housekeeping loci from a large… CONTINUE READING
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