The relative antioxidant activities of plant-derived polyphenolic flavonoids.

@article{Riceevans1995TheRA,
  title={The relative antioxidant activities of plant-derived polyphenolic flavonoids.},
  author={C. Rice-evans and Nicholas J. Miller and Paul G Bolwell and Peter M. Bramley and John B. Pridham},
  journal={Free radical research},
  year={1995},
  volume={22 4},
  pages={
          375-83
        }
}
The relative antioxidant activities, against radicals generated in the aqueous phase, of a range of plant-derived polyphenolic flavonoids, constituents of fruit, vegetables, tea and wine, have been assessed. The results show that compounds such as quercetin and cyanidin, with 3',4' dihydroxy substituents in the B ring and conjugation between the A and B rings, have antioxidant potentials four times that of Trolox, the vitamin E analogue. Removing the ortho-dihydroxy substitution, as in… 
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TLDR
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Model phenoxyl and more complex flavonoid radicals were generated by azide radical induced one-electron oxidation in aqueous solutions. Spectral, acid–base and redox properties of the radicals were
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The polyphenolic composition and antioxidant activity of the aerial parts of 18 medicinal or food plants of the As- teraceae family were studied. Five main caffeoyl derivatives were determined
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TLDR
All the flavonoids tested exhibited higher antioxidant efficacies against metal-ion- induced peroxidations than peroxyl-radical-induced peroxidation, suggesting that metal chelation may play a larger role in determining the antioxidant activities of these compounds than has previously been believed.
Glutathione and the Antioxidant Potential of Binary Mixtures with Flavonoids: Synergisms and Antagonisms
TLDR
The aim of this work was to predict a structure-antioxidant activity relationship using different classes of flavonoids and to assess, for the first time, possible synergisms and antagonisms with GSH.
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