The relationships among reproductive endpoints in Swiss mice, using the reproductive assessment by Continuous Breeding database.

@article{Chapin1997TheRA,
  title={The relationships among reproductive endpoints in Swiss mice, using the reproductive assessment by Continuous Breeding database.},
  author={Robert E. Chapin and Richard J. Sloane and Joseph K. Haseman},
  journal={Fundamental and applied toxicology : official journal of the Society of Toxicology},
  year={1997},
  volume={38 2},
  pages={129-42}
}
The database of Continuous Breeding mouse studies was evaluated to determine the relationships between the functional indicators of reproduction (pup measures) and the various necropsy endpoints collected for males and females. Of 72 chemicals studied, both males and females were affected in 33 studies, while females and/or conceptuses were affected in 7. Two compounds affected only males, 17 studies were negative, and in 13 studies with effects it was not possible to clearly determine the… CONTINUE READING

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