The relationship of the methylenetetrahydrofolate reductase C677T gene polymorphism in Turkish type 2 diabetic patients with and without nephropathy.

@article{Erolu2007TheRO,
  title={The relationship of the methylenetetrahydrofolate reductase C677T gene polymorphism in Turkish type 2 diabetic patients with and without nephropathy.},
  author={Zuhal Eroğlu and Mehmet Erdoğan and Aslı Tetik and Muamer Karadeniz and Sibel Cetinalp and Buket Kosova and Canan Gunduz and Ahmet G{\"o}khan Ozgen and Candeğer Yilmaz},
  journal={Diabetes/metabolism research and reviews},
  year={2007},
  volume={23 8},
  pages={621-4}
}
BACKGROUND Poor glycaemic control, hypertension and duration of diabetes are risk factors for the development of diabetic nephropathy, but there may be genetic factors. Recently, a common C to T mutation at nucleotide position 677 of the MTHFR gene (MTHFR677C > T) has been reported to be correlated with hyperhomocysteinemia and the severity of coronary artery disease as macroangiopathy. We aim to investigate Turkish type 2 diabetic patients with/without diabetic nephropathy and healthy group… CONTINUE READING

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