The relationship of the apolipoprotein E gene polymorphism Turkish Type 2 diabetic patients with and without nephropathy.

@article{Erdoan2009TheRO,
  title={The relationship of the apolipoprotein E gene polymorphism Turkish Type 2 diabetic patients with and without nephropathy.},
  author={Mehmet Erdoğan and Zuhal Eroğlu and Cigir Biray and Muamer Karadeniz and Sevki S Cetinkalp and Buket Kosova and Canan Gunduz and Nejat Topçuoğlu and Gokhan A Ozgen and Candeğer Yilmaz},
  journal={Journal of endocrinological investigation},
  year={2009},
  volume={32 3},
  pages={219-22}
}
OBJECTIVE Apolipoprotein E (ApoE) genetic variation which is a major constituent of plasma lipoproteins causes diabetic nephropathy progress. Chronic kidney disease is associated with increased E2 allele and the decreased E4 allele risk. The aim of this study was to investigate the association between ApoE gene polymorphism in the development of diabetic nephropathy in Type 2 diabetes Turkish patients. RESEARCH DESIGN AND METHODS The objective of the study is to investigate the influence of… CONTINUE READING