Corpus ID: 8910316

The relationship of secretin and somatostatin levels in plasma to glucose administration and acid secretion during fasting.

@article{Thuesen1987TheRO,
  title={The relationship of secretin and somatostatin levels in plasma to glucose administration and acid secretion during fasting.},
  author={B. Thuesen and O. B. Schaffalitzky de Muckadell and J. Holst and M. Bahnsen},
  journal={The American journal of gastroenterology},
  year={1987},
  volume={82 8},
  pages={
          723-6
        }
}
The concentrations of secretin and somatostatin in plasma were measured in 10 healthy subjects during a 4-day fast. The fast induced increased concentrations of plasma secretin (from 1.2 +/- 0.5 to 9.5 +/- 2.3 pmol/l) and somatostatin (from 5.2 +/- 1.5 to 8.6 +/- 1.7 pmol/l). Gastric aspiration for 1 h suppressed the high concentrations of secretin by 46% and somatostatin by 27%. The intravenous infusion of glucose reduced the plasma secretin even further by 88%; the decrease in somatostatin… Expand
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