The relationship of normal and abnormal microstructural proliferation to the mitral valve closure sound.

@article{Einstein2005TheRO,
  title={The relationship of normal and abnormal microstructural proliferation to the mitral valve closure sound.},
  author={Daniel R. Einstein and Karyn S. Kunzelman and Per G. Reinhall and Mark A. Nicosia and Richard P. Cochran},
  journal={Journal of biomechanical engineering},
  year={2005},
  volume={127 1},
  pages={134-47}
}
BACKGROUND Many diseases that affect the mitral valve are accompanied by the proliferation or degradation of tissue microstructure. The early acoustic detection of these changes may lead to the better management of mitral valve disease. In this study, we examine the nonstationary acoustic effects of perturbing material parameters that characterize mitral valve tissue in terms of its microstructural components. Specifically, we examine the influence of the volume fraction, stiffness and splay of… CONTINUE READING

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Mitral valve finite-element modelling from ultrasound data: a pilot study for a new approach to understand mitral function and clinical scenarios.

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