The relationship of hypovitaminosis D and IL-6 in preeclampsia.

@article{Xu2014TheRO,
  title={The relationship of hypovitaminosis D and IL-6 in preeclampsia.},
  author={Lai Xu and MinJae Lee and Arundhathi Jeyabalan and James M Roberts},
  journal={American journal of obstetrics and gynecology},
  year={2014},
  volume={210 2},
  pages={
          149.e1-7
        }
}
OBJECTIVE Vitamin D deficiency has been linked to the pathogenesis of preeclampsia. Given the demonstrated antiinflammatory function of vitamin D in multiple organ systems including trophoblast cells and placenta, we hypothesized that vitamin D deficiency contributes to the development of preeclampsia through increased inflammation, as indicated by elevated interleukin (IL)-6 concentrations. STUDY DESIGN Plasma samples from a large preeclampsia cohort study were examined in 100 preeclamptic… CONTINUE READING
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