The relationship of hypovitaminosis D and IL-6 in preeclampsia.

  title={The relationship of hypovitaminosis D and IL-6 in preeclampsia.},
  author={Lai Xu and MinJae Lee and Arundhathi Jeyabalan and James M Roberts},
  journal={American journal of obstetrics and gynecology},
  volume={210 2},
OBJECTIVE Vitamin D deficiency has been linked to the pathogenesis of preeclampsia. Given the demonstrated antiinflammatory function of vitamin D in multiple organ systems including trophoblast cells and placenta, we hypothesized that vitamin D deficiency contributes to the development of preeclampsia through increased inflammation, as indicated by elevated interleukin (IL)-6 concentrations. STUDY DESIGN Plasma samples from a large preeclampsia cohort study were examined in 100 preeclamptic… CONTINUE READING
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Publications referenced by this paper.
Showing 1-10 of 33 references

Longitudinal vitamin D status in pregnancy and the risk of pre-eclampsia.

BJOG : an international journal of obstetrics and gynaecology • 2012
View 3 Excerpts

Vitamin D and the regulation of placental inflammation

Liu, N.Q
J Immunol, • 2011
View 1 Excerpt

Effects of vitamin D3 on selected biochemical parameters of nutritional status, inflammation, and cardiovascular disease in patients undergoing long-term hemodialysis

A Bednarek-Skublewska
Pol Arch Med Wewn, • 2010
View 1 Excerpt

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