The relationship of copper to DNA damage and damage prevention in humans.

@article{Linder2012TheRO,
  title={The relationship of copper to DNA damage and damage prevention in humans.},
  author={Maria C. Linder},
  journal={Mutation research},
  year={2012},
  volume={733 1-2},
  pages={83-91}
}
Copper ions are well suited to facilitate formation of reactive oxygen species (ROS) that can damage biomolecules, including DNA and chromatin. That this can occur in vitro with isolated DNA or chromatin,or by exposure of cultured mammalian cells to copper complexed with various agents, has been well demonstrated. Whether that is likely to occur in vivo is not as clear. This review addresses the question of whether and how copper ions or complexes – in forms that could be present in vivo… CONTINUE READING
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Review of Copper Provision in the Parenteral Nutrition of Adults [Formula: see text].

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition • 2017
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