The relationship of adequate and excessive intake of vitamin D to health and disease.

@article{Holmes1983TheRO,
  title={The relationship of adequate and excessive intake of vitamin D to health and disease.},
  author={Ross Philip Holmes and Fred A. Kummerow},
  journal={Journal of the American College of Nutrition},
  year={1983},
  volume={2 2},
  pages={173-99}
}
Vitamin D is required for intestinal calcium and phosphorus absorption, kidney functions, bone synthesis, and possible vital functions in several other target tissues. Active forms of vitamin D are generated by hydroxylations, first in the liver and second in the kidney. The requirement for vitamin D is normally met by its synthesis in the skin. Inadequate skin exposure to sunlight, dark-pigmented skin, and a northern geographical latitude make some individuals susceptible to a deficiency. In… CONTINUE READING