The relationship of HLA-B and DR phenotypes to Behcet's syndrome, recurrent oral ulceration and the class of immune complexes.

@article{Lehner1982TheRO,
  title={The relationship of HLA-B and DR phenotypes to Behcet's syndrome, recurrent oral ulceration and the class of immune complexes.},
  author={Thomas Lehner and Kenneth I. Welsh and J. Richard Batchelor},
  journal={Immunology},
  year={1982},
  volume={47 4},
  pages={581-7}
}
A series of eighty Caucasian patients was divided into four groups with the mucocutaneous, arthritic, neurological and ocular types of Behcet's syndrome (BS) and a fifth group of patients with recurrent oral ulcers. The immunogenetic basis of the four types of BS was extended from HLA-B locus to the DR locus. Whereas B5 and more precisely the Bw51 split is the most discriminating marker of the ocular type of BS, DR7 also shows a significant increase in the ocular and neurological types. Indeed… CONTINUE READING