The relationship of DNA excision repair of ultraviolet-induced lesions to the maximum life span of mammals

@article{Francis1981TheRO,
  title={The relationship of DNA excision repair of ultraviolet-induced lesions to the maximum life span of mammals},
  author={A. A. Francis and W. H. Lee and J. Regan},
  journal={Mechanisms of Ageing and Development},
  year={1981},
  volume={16},
  pages={181-189}
}
Physical and chemical agents present in the environment can potentially damage mammalian DNA. Such damage is known in some cases to be repaired by the process of DNA excision repair. This process has been extensively studied utilizing the repair of ultraviolet irradiation damage as a model system. In this study we have used this system and the 5-bromodeoxyuridine photolysis assay to measure DNA excision repair in cells derived from 21 mammalian species. We have attempted to relate the DNA… Expand
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