The relationship of DNA and chromosome damage to survival of synchronized X-irradiated L5178Y cells. II. Repair.

@article{Wlodek1988TheRO,
  title={The relationship of DNA and chromosome damage to survival of synchronized X-irradiated L5178Y cells. II. Repair.},
  author={Danuta Wlodek and Walter N. Hittelman},
  journal={Radiation research},
  year={1988},
  volume={115 3},
  pages={566-75}
}
The purpose of this study was to investigate the role of DNA and chromosome repair in determining the difference in radiosensitivity between a radiosensitive murine leukemic lymphoblastoid cell line, L5178Y-S, and its radioresistant counterpart, L5178Y-R. Populations of cells in the G1 or G2 phase of the cell cycle were obtained by centrifugal elutriation and irradiated with X-ray doses up to 10 Gy and allowed to repair at 37 degrees C for various periods. The kinetics of DNA double-strand… CONTINUE READING

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