The relationship between the soluble Klotho protein and the residual renal function among peritoneal dialysis patients

@article{Akimoto2011TheRB,
  title={The relationship between the soluble Klotho protein and the residual renal function among peritoneal dialysis patients},
  author={Tetsu Akimoto and Kazuhiro Shiizaki and Taro Sugase and Yuko Watanabe and Hiromichi Yoshizawa and Naoko Otani and Akihiko Numata and Eri Takeshima and Tomoyuki Yamazaki and Takuya Miki and Chiharu Ito and Johanne V. Pastor and Yoshitaka Iwazu and Osamu Saito and Shigeaki Muto and Makoto Kuro-O and Eiji Kusano},
  journal={Clinical and Experimental Nephrology},
  year={2011},
  volume={16},
  pages={442-447}
}
Klotho has been investigated as an anti-aging protein that is predominantly expressed in the distal convoluted tubules in the kidneys and in the choroid plexus of the brain. The purpose of the present study was to determine the relationship between the soluble form of Klotho and renal function in chronic peritoneal dialysis (PD) patients, a relationship which remains poorly understood. The soluble Klotho levels in the serum, urine, and peritoneal dialysate obtained from thirty-six PD patients… CONTINUE READING

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