The relationship between the growth hormone and insulin-like growth factor axis in long-term survivors of childhood brain tumours.


OBJECTIVE We compared IGF-1 and IGFBP3 concentrations in a group of adults treated for brain tumours in childhood with those of matched controls, and investigated the relationship between the GH secretory pattern and IGF-1/IGFBP3 concentrations in the entire group. DESIGN We performed 24 h serum GH profiles using 20 minute sampling and measured… (More)


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