The relationship between the Rat Grimace Scale and mechanical hypersensitivity testing in three experimental pain models.

@article{Rantere2016TheRB,
  title={The relationship between the Rat Grimace Scale and mechanical hypersensitivity testing in three experimental pain models.},
  author={Debbie De Rantere and Christoph J. Schuster and Joseph Reimer and Daniel S J Pang},
  journal={European journal of pain},
  year={2016},
  volume={20 3},
  pages={417-26}
}
BACKGROUND The assessment of facial expressions associated with pain has been used to evaluate pain in humans and has recently found application in non-human mammals. These so called 'grimace scales' have the potential to be developed into a widely accepted non-invasive method of measuring pain in laboratory rodents. Currently, common methodologies to assess pain rely on nociceptive tests that assess stimulus evoked withdrawal responses. These tests, however, are limited to the assessment of a… CONTINUE READING

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