The relationship between synonymous codon usage and protein structure in Escherichia coli and Homo sapiens.

@article{Gu2004TheRB,
  title={The relationship between synonymous codon usage and protein structure in Escherichia coli and Homo sapiens.},
  author={Wanjun Gu and Tong Zhou and Jianmin Ma and Xiao Sun and Zuhong Lu},
  journal={Bio Systems},
  year={2004},
  volume={73 2},
  pages={89-97}
}
The role of silent position in the codon on the protein structure is an interesting and yet unclear problem. In this paper, 563 Homo sapiens genes and 417 Escherichia coli genes coding for proteins with four different folding types have been analyzed using variance analysis, a multivariate analysis method newly used in codon usage analysis, to find the correlation between amino acid composition, synonymous codon, and protein structure in different organisms. It has been found that in E. coli… CONTINUE READING

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