The relationship between structural brain imaging and histopathologic findings in schizophrenia research.

@article{Benes1993TheRB,
  title={The relationship between structural brain imaging and histopathologic findings in schizophrenia research.},
  author={Francine Mary Benes},
  journal={Harvard review of psychiatry},
  year={1993},
  volume={1 2},
  pages={
          100-9
        }
}
The suggestion that schizophrenia may involve a neurodegenerative process has emanated from the highly replicated finding of ventricular enlargement in brain images of patients with this disorder. These investigations have provided a direct impetus for recent histopathologic studies seeking evidence of a neurodegenerative process in the brains of subjects with schizophrenia. Whereas most postmortem studies have reported the presence of atrophy and/or neuronal loss in several corticolimbic… CONTINUE READING
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