The relationship between risk factor levels and presence of coronary artery calcification is dependent on apolipoprotein E genotype.

@article{Kardia1999TheRB,
  title={The relationship between risk factor levels and presence of coronary artery calcification is dependent on apolipoprotein E genotype.},
  author={Sharon L. Kardia and Martha Haviland and Robert E. Ferrell and Charles F. Sing},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={1999},
  volume={19 2},
  pages={427-35}
}
An important research question in the study of the genetics of coronary artery disease (CAD) is whether information about genetic variation will improve our ability to predict CAD beyond established risk factors. This question is especially relevant to the goal of identifying young, asymptomatic adults with coronary atherosclerosis who would benefit most from interventions to reduce risk. Coronary artery calcification (CAC) detected by electron-beam computed tomography is a relatively new… CONTINUE READING
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