The relationship between resting blood pressure and acute pain sensitivity in healthy normotensives and chronic back pain sufferers: the effects of opioid blockade.

@article{Bruehl2002TheRB,
  title={The relationship between resting blood pressure and acute pain sensitivity in healthy normotensives and chronic back pain sufferers: the effects of opioid blockade.},
  author={Stephen P. Bruehl and Ok Yung Chung and Pamela P. Ward and Benjamin A Johnson and James A. McCubbin},
  journal={Pain},
  year={2002},
  volume={100 1-2},
  pages={191-201}
}
Resting blood pressure is inversely correlated with acute pain sensitivity in healthy normotensives. This study tested: (1) whether endogenous opioid activity is necessary for this adaptive relationship to occur, (2) whether this relationship is altered in chronic low back pain (LBP), and (3) whether endogenous opioid dysfunction underlies any such alterations. Fifty-one pain-free normotensives and 44 normotensive chronic LBP sufferers received opioid blockade (8 mg naloxone i.v.) or placebo… CONTINUE READING

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