The relationship between prostate inflammation and lower urinary tract symptoms: examination of baseline data from the REDUCE trial.

@article{Nickel2008TheRB,
  title={The relationship between prostate inflammation and lower urinary tract symptoms: examination of baseline data from the REDUCE trial.},
  author={John Curtis Nickel and Claus G. Roehrborn and Michael P O'Leary and David G. Bostwick and Matthew C Somerville and Roger S Rittmaster},
  journal={European urology},
  year={2008},
  volume={54 6},
  pages={1379-84}
}
OBJECTIVE The ongoing REDUCE trial is a 4-yr, phase 3, placebo-controlled study to determine if daily dutasteride 0.5mg reduces the risk of biopsy detectable prostate cancer. Prostate biopsies performed in all men prior to entry were centrally reviewed, thus allowing an examination of the relationship between inflammatory changes and lower urinary tract symptoms (LUTS). METHODS Eligible men were aged 50-75 yr, with serum prostate-specific antigen >or=2.5 ng/ml and <or=10 ng/ml (50-60 yr), or… CONTINUE READING
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The relationship between prostate inflammation and lower urinary tract symptoms: examination of baseline data from the REDUCE trial

JC Nickel, CG Roehborn, MP O’Leary
Eur Urol. In press • 2007
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