The relationship between microsatellite slippage mutation rate and the number of repeat units.

@article{Lai2003TheRB,
  title={The relationship between microsatellite slippage mutation rate and the number of repeat units.},
  author={Yinglei Lai and Fengzhu Sun},
  journal={Molecular biology and evolution},
  year={2003},
  volume={20 12},
  pages={2123-31}
}
Microsatellite markers are widely used for genetic studies, but the relationship between microsatellite slippage mutation rate and the number of repeat units remains unclear. In this study, microsatellite distributions in the human genome are collected from public sequence databases. We observe that there is a threshold size for slippage mutations. We consider a model of microsatellite mutation consisting of point mutations and single stepwise slippage mutations. From two sets of equations… CONTINUE READING

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