The relationship between glycemic control and plasma vascular endothelial growth factor and endothelin-1 concentration in diabetic patients.

@article{Kakizawa2004TheRB,
  title={The relationship between glycemic control and plasma vascular endothelial growth factor and endothelin-1 concentration in diabetic patients.},
  author={Hiroaki Kakizawa and Mitsuyasu Itoh and Yasutoshi Itoh and Shigeo Imamura and Yoko Ishiwata and Takashi Matsumoto and Keiko Yamamoto and Taiya Kato and Yasunaga Ono and Mutsuko Nagata and Nobuki Hayakawa and Atsushi Suzuki and Yoshie Goto and Naohisa Oda},
  journal={Metabolism: clinical and experimental},
  year={2004},
  volume={53 5},
  pages={550-5}
}
Understanding the causes of diabetic vascular complications has become an increasingly important issue because of the rapidly rising prevalence of diabetes. Recently discovered vasoconstrictors and angiogenesis regulators, such as endothelin (ET) and vascular endothelial growth factor (VEGF), have been intensely studied for possible pathogenic roles in diabetic vascular complications. The present study was undertaken to clarify the effect of glycemic control on serum VEGF and plasma ET-1… CONTINUE READING