The relationship between estimated sodium and potassium excretion and subsequent renal outcomes.

@article{Smyth2014TheRB,
  title={The relationship between estimated sodium and potassium excretion and subsequent renal outcomes.},
  author={Andrew Smyth and Daniela Dunkler and Peggy Gao and Koon Kang Teo and Salim Yusuf and Martin J O'Donnell and Johannes F. E. Mann and Catherine M. Clase},
  journal={Kidney international},
  year={2014},
  volume={86 6},
  pages={1205-12}
}
Patients are often advised to reduce sodium and potassium intake, but supporting evidence is limited. To help provide such evidence we estimated 24 h urinary sodium and potassium excretion in 28,879 participants at high cardiovascular risk who were followed for a mean of 4.5 years in the ONTARGET and TRANSCEND trials. The primary outcome was eGFR decline of 30% or more or chronic dialysis. Secondary outcomes were eGFR decline of 40% or more or chronic dialysis, doubling of serum creatinine or… CONTINUE READING
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