The relationship between contraction and intracellular sodium in rat and guinea-pig ventricular myocytes.

@article{Harrison1992TheRB,
  title={The relationship between contraction and intracellular sodium in rat and guinea-pig ventricular myocytes.},
  author={Sally M. Harrison and Elaine Teresa McCall and Mark R. Boyett},
  journal={The Journal of physiology},
  year={1992},
  volume={449},
  pages={517-50}
}
1. The contraction, measured optically, and the intracellular Na+ activity (aNai), measured with the Na(+)-sensitive fluorescent dye SBFI, have been recorded simultaneously in rat and guinea-pig ventricular myocytes. 2. In rat and guinea-pig ventricular myocytes at rest, aNai was 7.8 +/- 0.3 mM (n = 4) and 5.1 +/- 0.3 mM (n = 16), respectively. 3. When both rat and guinea-pig ventricular myocytes were stimulated at 1 Hz after a rest there was usually a gradual increase in twitch shortening… CONTINUE READING

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