The relationship between cognitive and brain changes in posttraumatic stress disorder.

@article{Bremner2006TheRB,
  title={The relationship between cognitive and brain changes in posttraumatic stress disorder.},
  author={J. Douglas Bremner},
  journal={Annals of the New York Academy of Sciences},
  year={2006},
  volume={1071},
  pages={80-6}
}
Preclinical studies show that stress is associated with changes in structure of the hippocampus, a brain area that plays a critical role in memory, inhibition of neurogenesis, and memory deficits. Studies in animals showed that both serotonin reuptake inhibitors (SSRIs) and the epilepsy medication phenytoin (dilantin) block the effects of stress on the hippocampus. Imaging studies in posttraumatic stress disorder (PTSD) have found smaller volume of the hippocampus as measured with magnetic… CONTINUE READING