The relationship between coagulation state and inflammatory bowel disease: current understanding and clinical implications.

@article{Koutroubakis2015TheRB,
  title={The relationship between coagulation state and inflammatory bowel disease: current understanding and clinical implications.},
  author={Ioannis E. Koutroubakis},
  journal={Expert review of clinical immunology},
  year={2015},
  volume={11 4},
  pages={479-88}
}
Inflammatory bowel disease (IBD) is associated with a hypercoagulable state and subsequently with an increased risk for venous thromboembolism (VTE). VTE in IBD is characterized by a high recurrence rate and is associated with the disease activity. Acquired endothelial dysfunction, abnormalities of platelets, activation of coagulation system and impaired fibrinolysis are the main changes in the coagulation state in IBD. The development of VTE in IBD has been considered to be the result of… CONTINUE READING