The relationship between chromosomal abnormality in the human preimplantation embryo and development in vitro.

@article{Almeida1996TheRB,
  title={The relationship between chromosomal abnormality in the human preimplantation embryo and development in vitro.},
  author={Paula A. Almeida and Virginia Noelle Bolton},
  journal={Reproduction, fertility, and development},
  year={1996},
  volume={8 2},
  pages={
          235-41
        }
}
The relationship between the survival of the human preimplantation embryo in vitro and chromosomal abnormality was investigated by cytogenetic analysis of a total of 250 embryos of varying morphology between the pronucleate stage and the 8-cell stage. The overall incidence of chromosomal abnormality among these embryos was 49%. At the pronucleate stage (n = 46) the incidence was 65.2%, at the 2-4-cell stage (n = 126) it was 54.6%, and at the 5-8-cell stage (n = 78) it was 27.4%. Cleavage-stage… CONTINUE READING

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