The relationship between chondroprotective and antiinflammatory effects of Withania somnifera root and glucosamine sulphate on human osteoarthritic cartilage in vitro.

@article{Sumantran2008TheRB,
  title={The relationship between chondroprotective and antiinflammatory effects of Withania somnifera root and glucosamine sulphate on human osteoarthritic cartilage in vitro.},
  author={Venil N. Sumantran and Rucha Chandwaskar and Asavari Kulkarni Joshi and Sanjay V. Boddul and Bhushan Patwardhan and Arvind Chopra and Ulhas V. Wagh},
  journal={Phytotherapy research : PTR},
  year={2008},
  volume={22 10},
  pages={1342-8}
}
Using a validated explant model of in vitro cartilage damage, the effects of aqueous extracts of Withania somnifera (Ashwagandha) root and glucosamine sulphate (GlcS) were tested on the levels of nitric oxide (NO) and glycosaminoglycans (GAGs) secreted by knee cartilage from chronic osteoarthritis (OA) patients. W. somnifera extracts significantly decreased… CONTINUE READING