• Biology, Medicine
  • Published in
    Environmental toxicology and…
    2007
  • DOI:10.1897/06-459R.1

The relationship between cholinesterase inhibition and two types of swimming performance in chlorpyrifos-exposed coho salmon (Oncorhynchus kisutch).

@article{Tierney2007TheRB,
  title={The relationship between cholinesterase inhibition and two types of swimming performance in chlorpyrifos-exposed coho salmon (Oncorhynchus kisutch).},
  author={Keith B. Tierney and Matt Casselman and Scott Takeda and Tony J. Farrell and Chris B. Kennedy},
  journal={Environmental toxicology and chemistry},
  year={2007},
  volume={26 5},
  pages={
          998-1004
        }
}
Brain acetylcholinesterase (AChE) activity was evaluated after two different swimming tests in coho salmon (Oncorhynchus kisutch; 238 +/- 5 g) given 96-h exposures to 0, 5, 10, 20, or 40 microg/L of chlorpyrifos. Brain AChE activity decreased in a concentration-dependent manner (AChE activities were 81.8, 52.2, 37.3, and 21.3% of control for the 5, 10, 20, and 40 microg/L exposures, respectively), whereas swimming performance was impaired after a threshold of AChE impairment was reached… CONTINUE READING

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