The relationship between bone-loss of steroid-induced osteonecrosis and local expression of OPG/OCIF.

OBJECTIVE To probe the relationship between the osteoprotegerin/osteoclastogenesis inhibitory factor (OPG/OCIF) expression of bone and the relative bone-loss. METHODS Steroid-induced osteonecrosis-model was reproduced in thirty-one new Zealand hares, and 24 ones were alive 3 days after administration of endotoxin and methylprednisolone. The alive… CONTINUE READING