The relationship between blood flow and neuronal activity in the rodent olfactory bulb.

@article{Chaigneau2007TheRB,
  title={The relationship between blood flow and neuronal activity in the rodent olfactory bulb.},
  author={Emmanuelle Chaigneau and Pascale Tiret and J. C. Lecoq and Mathieu Ducros and Thomas Kn{\"o}pfel and Serge Charpak},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2007},
  volume={27 24},
  pages={6452-60}
}
In the brain, neuronal activation triggers an increase in cerebral blood flow (CBF). Here, we use two animal models and several techniques (two-photon imaging of CBF and neuronal calcium dynamics, intracellular and extracellular recordings, local pharmacology) to analyze the relationship between neuronal activity and local CBF during odor stimulation in the rodent olfactory bulb. Application of glutamate receptor antagonists or tetrodotoxin directly into single rat olfactory glomeruli blocked… CONTINUE READING

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