The relationship between bispectral index and targeted propofol concentration is biphasic in patients with major burns.

Abstract

BACKGROUND Many pathophysiologic alterations in major burns can cause changes in the distribution of, and perhaps response to, drugs commonly used in anesthesia practice. This study was conducted to assess changes in bispectral index (BIS) caused by increasing the target propofol effect-site concentration during a target-controlled infusion (TCI) in major… (More)

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