The relationship between bispectral index and targeted propofol concentration is biphasic in patients with major burns.

@article{Han2005TheRB,
  title={The relationship between bispectral index and targeted propofol concentration is biphasic in patients with major burns.},
  author={Taehyung Han and J-W Lee and In-Suk Kwak and H-Y Kil and K-W Han and Kyonsong Kim},
  journal={Acta anaesthesiologica Scandinavica},
  year={2005},
  volume={49 1},
  pages={
          85-91
        }
}
BACKGROUND Many pathophysiologic alterations in major burns can cause changes in the distribution of, and perhaps response to, drugs commonly used in anesthesia practice. This study was conducted to assess changes in bispectral index (BIS) caused by increasing the target propofol effect-site concentration during a target-controlled infusion (TCI) in major burns. METHODS Eighteen patients, ASA physical status 2 or 3, aged from 20 to 55 years old, weighing 50-70 kg, with major burns, scheduled… CONTINUE READING