The relationship between arterial po2 and cerebral blood flow in hypoxic hypoxia.

@article{Borgstrm1975TheRB,
  title={The relationship between arterial po2 and cerebral blood flow in hypoxic hypoxia.},
  author={Lars Borgstr{\"o}m and Haraldur J{\'o}hannsson and Bo K. Siesj{\"o}},
  journal={Acta physiologica Scandinavica},
  year={1975},
  volume={93 3},
  pages={423-32}
}
The relationship between arterial oxygen tension (PaO2) and cerebral blood flow (CBF) in hypoxic hypoxia was studied in artificially ventilated and normocapnic rats. Changes in CBF were evaluated from arteriovenous differences in oxygen content after 2, 5, 15 and 30 min exposure to PaO2 85, 75, 55, 45, 35, and 25 mm Hg. In separate experiments the PaO2 was decreased to 25 mm Hg for 1, 2, 5, 15 and 30 min in animals in which PaCO2 was allowed to fall by 5-10 mm Hg. There was a small, gradual… CONTINUE READING
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