The relationship between angiotensinogen gene polymorphisms and essential hypertension in a Northern Han Chinese population.

@article{Li2014TheRB,
  title={The relationship between angiotensinogen gene polymorphisms and essential hypertension in a Northern Han Chinese population.},
  author={Hongmei Li and Zhirong Du and Lin Zhang and Tong Wu and Zhihui Deng and Jingping Li and Mingyu Cong and Jicheng Liu and Changchun Qiu},
  journal={Angiology},
  year={2014},
  volume={65 7},
  pages={614-9}
}
Gene polymorphisms of the renin-angiotensin system are involved in the pathophysiology of hypertension. We genotyped 4 polymorphisms of angiotensinogen (AGT) gene A-20C (rs5050), A-6G (rs5051), C3889T (rs4762), and C4072T (rs699) by polymerase chain reaction-restriction fragment length polymorphism in 652 patients and 780 controls to examine the association of AGT and hypertension in a Northern Han Chinese population. There were significant differences in the distribution of genotypes and… CONTINUE READING

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