The regulatory roles of the galactose permease and kinase in the induction response of the GAL network in Saccharomyces cerevisiae.

@article{Hawkins2006TheRR,
  title={The regulatory roles of the galactose permease and kinase in the induction response of the GAL network in Saccharomyces cerevisiae.},
  author={Kristy M Hawkins and Christina D. Smolke},
  journal={The Journal of biological chemistry},
  year={2006},
  volume={281 19},
  pages={13485-92}
}
The GAL genetic switch of Saccharomyces cerevisiae exhibits an ultrasensitive response to the inducer galactose as well as the "all-or-none" behavior characteristic of many eukaryotic regulatory networks. We have constructed a strain that allows intermediate levels of gene expression from a tunable GAL1 promoter at both the population and the single cell level by altering the regulation of the galactose permease Gal2p. Similar modifications to other feedback loops regulating the Gal80p… CONTINUE READING

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Engineered GAL Network 13492 JOURNAL OF BIOLOGICAL CHEMISTRY VOLUME

  • J. B. Thoden, C. A. Sellick, D. J. Timson, R. J. Reece, H. M. andHolden
  • J. Biol. Chem. 280,
  • 2005
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