The regulatory role of nickel on H3K27 demethylase JMJD3 in kidney cancer cells.

@article{Guo2016TheRR,
  title={The regulatory role of nickel on H3K27 demethylase JMJD3 in kidney cancer cells.},
  author={Xiaoqiang Guo and Yanmin Zhang and Qiang Zhang and Pingping Fa and Yaoting Gui and Guoquan Gao and Zhi-Ming Cai},
  journal={Toxicology and industrial health},
  year={2016},
  volume={32 7},
  pages={
          1286-92
        }
}
Nickel compounds are an important class of environmental pollutants and carcinogens. Chronic exposure to nickel compounds has been connected with increased risks of numerous cancers, including lung and kidney cancers. But the precise mechanism by which nickel compounds exert their carcinogenic properties is not completely understood. In this study, kidney cancer cells namely human embryonic kidney 293-containing SV40 large T-antigen (HEK293T) and 786-0 were incubated with various concentrations… CONTINUE READING

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