The regulatory role of α-synuclein and parkin in neuronal cell apoptosis; possible implications for the pathogenesis of Parkinson’s disease

Abstract

Parkinson’s disease (PD) is the second most common progressive neurodegenerative disorder beyond Alzheimer’s disease, affecting approximately 1% of people over the age of 65. The major pathological hallmarks of PD are significant loss of nigrostriatal dopaminergic (DA) neurons and the presence of intraneuronal protein inclusions termed Lewy bodies. Sporadic… (More)
DOI: 10.1007/s10495-010-0486-8

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@article{Yasuda2010TheRR, title={The regulatory role of α-synuclein and parkin in neuronal cell apoptosis; possible implications for the pathogenesis of Parkinson’s disease}, author={Toru Yasuda and Hideki Mochizuki}, journal={Apoptosis}, year={2010}, volume={15}, pages={1312-1321} }