The regulatory network of E. coli metabolism as a Boolean dynamical system exhibits both homeostasis and flexibility of response

@article{Samal2007TheRN,
  title={The regulatory network of E. coli metabolism as a Boolean dynamical system exhibits both homeostasis and flexibility of response},
  author={Areejit Samal and Sanjay Jain},
  journal={BMC Systems Biology},
  year={2007},
  volume={2},
  pages={21 - 21}
}
Elucidating the architecture and dynamics of large scale genetic regulatory networks of cells is an important goal in systems biology. We study the system level dynamical properties of the genetic network of Escherichia coli that regulates its metabolism, and show how its design leads to biologically useful cellular properties. Our study uses the database (Covert et al., Nature 2004) containing 583 genes and 96 external metabolites which describes not only the network connections but also the… CONTINUE READING

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