The regulation of oxytocin gene expression in early bovine luteal cells.

@article{Furuya1990TheRO,
  title={The regulation of oxytocin gene expression in early bovine luteal cells.},
  author={Keizo Furuya and Craig Alexander McArdle and Richard Ivell},
  journal={Molecular and cellular endocrinology},
  year={1990},
  volume={70 1},
  pages={81-8}
}
The oxytocin gene is maximally expressed in the cells of the early bovine corpus luteum (1-5 days post-ovulation) and provides an excellent marker for luteinization, having been up-regulated in vivo at ovulation. However, it is down-regulated again later in the luteal phase. To help understand the mechanisms involved in regulating this gene, and hence differentiation in the early bovine corpus luteum, oxytocin secretion into the medium as well as oxytocin mRNA were measured in serum-free… CONTINUE READING