The regulation of intracellular transport of cholesterol in bovine adrenal cells: purification of a novel protein.

@article{Yanagibashi1988TheRO,
  title={The regulation of intracellular transport of cholesterol in bovine adrenal cells: purification of a novel protein.},
  author={K Yanagibashi and Yasuo Ohno and Masaru Kawamura and P. F. Hall},
  journal={Endocrinology},
  year={1988},
  volume={123 4},
  pages={2075-82}
}
We have purified to homogeneity a protein from bovine adrenal (fasciculata) cells that is capable of: 1) stimulating synthesis of pregnenolone (in a concentration-dependent fashion) by mitochondria when added with exogenous cholesterol; 2) increasing the concentration of cholesterol in outer and inner membrane when added to mitochondria with exogenous cholesterol; 3) increasing the rate of transport of cholesterol from outer membrane to inner membrane when the two membranes are incubated… CONTINUE READING
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