The regulation of HIV-1 gene expression: the emerging role of chromatin.

@article{He2002TheRO,
  title={The regulation of HIV-1 gene expression: the emerging role of chromatin.},
  author={Guocheng He and Loyda Ylisastigui and David M Margolis},
  journal={DNA and cell biology},
  year={2002},
  volume={21 10},
  pages={697-705}
}
Host and viral factors that regulate the expression of the human immunodeficiency virus type 1 (HIV-1) 5' long terminal repeat (LTR) promoter have been studied since the recognition that HIV is the cause of the acquired immunodeficiency syndrome (AIDS). However, complex modifications of nucleosomes within chromatin has been recently recognized as an important mechanism of gene regulation. Nucleosome remodelling can alter the accessibility of DNA to specific activators or repressors, general… CONTINUE READING

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