The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver
@article{Li1993TheRE, title={The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver}, author={Y. Li and K. Hayakawa and R. Hardy}, journal={The Journal of Experimental Medicine}, year={1993}, volume={178}, pages={951 - 960} }
The expression of B lineage associated genes during early B cell differentiation stages is not firmly established. Using cell surface markers and multiparameter flow cytometry, bone marrow (BM) cells can be resolved into six fractions, representing sequential stages of development; i.e., pre-Pro-B, early Pro-B, late Pro-B/large Pre-B, small Pre-B, immature B, and mature B cells. Here we quantitate the levels of several B lineage associated genes in each of these fractions by RT-PCR… CONTINUE READING
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