The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver

@article{Li1993TheRE,
  title={The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver},
  author={Y. Li and K. Hayakawa and R. Hardy},
  journal={The Journal of Experimental Medicine},
  year={1993},
  volume={178},
  pages={951 - 960}
}
  • Y. Li, K. Hayakawa, R. Hardy
  • Published 1993
  • Biology, Medicine
  • The Journal of Experimental Medicine
  • The expression of B lineage associated genes during early B cell differentiation stages is not firmly established. Using cell surface markers and multiparameter flow cytometry, bone marrow (BM) cells can be resolved into six fractions, representing sequential stages of development; i.e., pre-Pro-B, early Pro-B, late Pro-B/large Pre-B, small Pre-B, immature B, and mature B cells. Here we quantitate the levels of several B lineage associated genes in each of these fractions by RT-PCR… CONTINUE READING
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