The regenerative capacity of the zebrafish heart is dependent on TGFβ signaling.


Mammals respond to a myocardial infarction by irreversible scar formation. By contrast, zebrafish are able to resolve the scar and to regenerate functional cardiac muscle. It is not known how opposing cellular responses of fibrosis and new myocardium formation are spatially and temporally coordinated during heart regeneration in zebrafish. Here, we report… (More)
DOI: 10.1242/dev.078543


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