The reduction of postlaminectomy peridural fibrosis in rabbits by a carbohydrate polymer.

@article{Robertson1993TheRO,
  title={The reduction of postlaminectomy peridural fibrosis in rabbits by a carbohydrate polymer.},
  author={J. Robertson and A. Meriç and F. Dohan and J. Schweitzer and J. Wujek and S. Ahmad},
  journal={Journal of neurosurgery},
  year={1993},
  volume={79 1},
  pages={
          89-95
        }
}
Spinal peridural fibrosis following total laminectomy in New Zealand White rabbits was significantly decreased by the intraoperative application of GT1587, a semi-synthetic carbohydrate polymer. The application of a similar polymer, GT1043, or phosphate-buffered saline (PBS) was not as effective. Laminectomies were performed at L-2 and L-4 in 25 rabbits. Absorbable gelatin sponge soaked with GT1043, GT1587, or PBS was applied in a blinded fashion to the operative sites, with untreated (sham… Expand
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